I spent a little time this morning upgrading a Domino server from 10.0 to 10.0.1. Upgrading Domino, Traveler and Verse on Prem took about 15 minutes. Got to love those simple upgrades. Only wish some other products were that simple.
That isn't to say there wasn't any issue. This was a Windows box and when the Domino service started, it failed with an error. Event viewer said the error number was 7024, but didn't offer any help at all. I re-ran the Domino install and after that the server started without any issue. I'm guessing it's something to do with the Traveler install.
One note on Verse on Prem - the “install” is down from about 20 files to about 5 now. So don't be surprised when you unzip the install file and only see that small number. That's how it's supposed to be! The documentation does say that, but who reads documentation! :)